Irmos: Wherefore hast Thou turned Thy face from me, O Light never-waning? And why hath a strange darkness covered me, wretch that I am? But turn me, and guide my steps to the light of Thy commandments, I pray.
Thou didst offer thyself to Christ thy Master as a perfect and unblemished sacrifice, and, slain in thy zeal, thou didst shed thy blood, O Isidore, sharing in His suffering and becoming a worthy heir of His kingdom.
Theotokion: Human nature, which had been defiled by disobedience in the beginning and grievously corrupted, becoming mortal, hast thou restored, O all-immaculate Mistress Theotokos who in manner past understanding gavest birth to the Wellspring of immortality.
Strengthened by Thine omnipotent might, O Savior, the right victorious martyr Isidore did away with the gloom of deception; for, beheaded, he right laudably committed his soul to Thee, the Bestower of light, O Master.
The Church of Christ is adorned with thy precious blood and made luminous by thy sufferings through thine opposition to sin, O glorious one; for thou didst mightily contend against it even to the shedding of thy blood, O Isidore.
Translated by Isaac Lambertsen. Edition menaion.en.lambertsen.